Features of Endran Healer

1. Same Ingredients, Reasonable Cost

→ By utilizing salmon-derived PN ingredients, similar to ReXran, we aim for similar improvements while reducing the cost burden.

2. Beyond Simple Injection, Precise Treatment Planning

→ We inject PN into the appropriate layer and depth, tailored to the skin's structure, aiming for efficient improvement.

3. Treatment Accuracy Confirmed by Wheal Formation

→ We check the accuracy of drug injection by confirming the wheal formation that appears immediately after the procedure with the patient.

4. Consultation and Treatment Directly Performed by the Director

→ We thoroughly diagnose the patient's skin condition and history, and conduct 1:1 customized treatments.

5. Minimize Irritation, Support Recovery Process

→ We use a Jaungo modeling mask to gently soothe and help even sensitive skin recover.

6. Customized Wheal Spacing Adjustment by Area

→ For the cheeks and forehead, we use spacing optimized for efficient improvement, while for the eye and mouth areas, we apply it more densely. We adjust the spacing considering skin thickness, elasticity, and wrinkle direction. Even for the same 2cc or 4cc treatments, our clinic approaches them with subtle differences.

What are the advantages of Endran Healer?

1. Same Ingredients, Reasonable Choice

As the patent for ReXran's PN ingredient (Polynucleotide) has expired, similar salmon-derived PN-based products are emerging in the market.

Endran Healer also contains the same ingredients,

and offers the advantage of being able to receive treatment at a more reasonable cost.

It is a realistic PN solution that offers skin improvement while reducing the price burden,

and if cost-efficiency is important to you, Endran Healer can be a good alternative.

2. Precision of Treatment, as Important as Ingredients

The mere presence of PN ingredients does not guarantee identical results for all treatments.

Endran Healer treatment is more than just injecting medication;

it requires precise injection into the correct skin layer, at the appropriate depth, and with the calculated necessary amount.

We carefully adjust the injection depth for each layer, meticulously considering the patient's skin thickness, degree of damage, and even pore structure.

This precision can induce dermal remodeling and collagen regeneration, positively impacting skin improvement.

3. “The medication has reached its target” – Confirming Wheals Together

At our clinic, we ensure that the PN ingredients have been properly injected through a process

where both the medical staff and the patient visually confirm it.

The wheal formation that appears after the procedure is not just a simple reaction, but an important indicator that the medication has properly reached the target area.

→ We confirm and explain the wheal formation with the patient immediately after the procedure.

We carefully approach this, believing that a brief wheal check time can positively impact long-term results.

4. From Consultation to Treatment, 1:1 with the Director

You won't find generic explanations provided by a consultation manager at our clinic.

All information, including the patient's skin condition, sensitivity, past treatment experiences, and currently used products,

is thoroughly understood by the director personally, from start to finish.

This helps PN work more effectively on the skin.

Furthermore, it helps to proactively reduce the possibility of unexpected inflammation or side effects.

5. Minimize Irritation and Support the Recovery Process.

At our clinic, applying a Jaungo modeling mask after PN treatment is included as a standard procedure.

To quickly soothe discomforts such as heat sensation, redness, and hypersensitivity, we also apply oriental soothing management.

This can help to pre-regulate the skin's excessive immune response.

Thanks to this, even individuals with thin or sensitive skin can consider PN treatment.

We also consider the recovery process after the procedure to be important, and provide meticulous care.

6. Embo spacing is planned considering the characteristics of each area.

During Endranhiller treatment, both the injection site and the injection interval are carefully considered and determined.

For areas with a thick and relatively wide dermis, such as the cheeks or forehead,

Even if the PN ingredient is injected at one point, it can spread widely, so improvement can be expected even with treatment at 1~1.5cm intervals.

However, the skin around the eyes and mouth is thin and wrinkles are concentrated,

treating more delicately at 0.5cm intervals can help refine the skin texture.

If the skin is thin and has many sunken areas, or

if the skin texture structure has become irregular due to laser treatments, etc., the injection method may be adjusted with relatively dense intervals even on the cheeks or forehead.

In this procedure, we thoroughly understand the skin thickness, elasticity, wrinkle direction, and purpose of the treatment,

and meticulously plan the embo injection site and interval on a 1:1 basis.

Even if the same amount is used, different results can be expected depending on the treatment method.

One of the characteristics of Endranhiller treatment is that it aims for a customized approach for each patient, rather than merely mechanical injection.

How can Endranhiller help?

1. It contributes to making the skin firmer by stimulating collagen & elastin production.

The PN (Polynucleotide) component extracted from salmon affects fibroblasts in the skin's dermis,

and can promote the production of collagen and elastin.

Consequently, an increase in skin thickness, improvement in fine wrinkles, and restoration of elasticity can be expected.

Along with this, pore improvement can also be expected.

2. It helps restore damaged skin barriers and contributes to enhancing the skin's natural strength.

PN promotes the secretion of various growth factors such as TGF and FGF, which can positively impact epidermal cell regeneration and skin barrier recovery.

As a result, it can help improve inner dryness, reduce sensitivity, and enhance the skin's natural regenerative power.

It can be particularly beneficial for soothing and recovery processes of sensitized skin after laser or peeling treatments.

3. Naturally improving skin condition changes

Endranhiller is not a treatment that creates volume like fillers or controls muscle movement like Botox.

Through this, you can experience the skin regaining its natural health, with smoother skin texture, reduced inner dryness, and improved makeup adherence.

For those who desire overall skin improvement without noticeable changes, Endranhiller treatment can be considered.

Endranhiller Mechanism of Action

1. Activates fibroblasts to induce fundamental structural improvement of the skin.

PN (Polynucleotide), the main ingredient of Endranhiller,

is a high-purity DNA fragment obtained from salmon, and when injected into the skin's dermis,

it acts like a damage signal, playing a role in activating fibroblasts.

These fibroblasts help produce skin components such as collagen, elastin, and hyaluronic acid,

and can make a significant contribution to making the skin structure more firm and elastic.

2. Promotes the secretion of growth factors to help maintain a healthy skin state.

Activated fibroblasts subsequently influence the secretion of various growth factors.

TGF-β: Plays a role in promoting collagen synthesis.

FGF can positively impact the regeneration of skin cells and the recovery of damaged areas.

VEGF helps facilitate the circulation of micro-vessels within the skin, aiding in nutrient supply.

These growth factors contribute to creating an environment where the skin can regenerate itself.

Through this, we can expect to help the self-recovery of damaged epidermis and skin barrier function.

As a result, you may experience changes such as reduced skin sensitivity, improved inner dryness, and enhanced overall recovery.

3. Dermal Density Improvement: Expecting Skin Replenishment

EndranHiller is a treatment that focuses on and acts upon the dermis, a crucial part of skin health.

The polynucleotide (PN) component helps reconstruct the extracellular matrix (ECM), excluding major components like collagen, elastin, and hyaluronic acid, which form the dermal layer.

This allows us to expect an effect of increased density of collagen, hyaluronic acid, and proteins within the dermal tissue, leading to a more densely filled appearance.

As a result, it can help improve skin's inner elasticity, alleviate fine wrinkles or sunken areas, and create a skin condition where the skin texture is smoothed, allowing makeup to adhere well.

4. Reduced Skin Irritation and Soothing Effect Supporting the Recovery Process

In addition to supporting the skin's regeneration process, PN can contribute to managing subtle inflammatory reactions within the skin.

When chronic redness appears,

Skin that reacts sensitively to external stimuli,

Temporary sensitivity appearing after laser treatment, etc.

In such cases, it can help reduce excessive inflammatory reactions and promote the skin's normal recovery.

Therefore, EndranHiller is a polynucleotide (PN) treatment method that even those with sensitive skin can consider with less burden.

EndranHiller Treatment Procedure

1. Precise Skin Diagnosis

By carefully assessing each individual's skin thickness, elasticity, and sensitivity,

We meticulously plan at what depth and with what injection method the polynucleotide (PN) component will be delivered.

2. 1:1 In-depth Consultation with the Director

The area desired for improvement and the scope of treatment required

Our medical staff will directly diagnose your condition and create a personalized treatment plan.

We establish customized treatment plans that consider each individual's skin characteristics, rather than standardized consultation methods.

3. Anesthetic Cream Application

As PN injection is a procedure directly performed on the dermal layer,

We ensure sufficient application time for anesthetic cream, about 20-30 minutes before the procedure,

To minimize any discomfort that may occur during the treatment.

4. EndranHiller Injection Procedure

The PN component is precisely injected, considering the pre-planned depth and location.

The injection site is immediately confirmed by the resulting 'embossing' phenomenon after injection,

And if necessary, adjustments are made immediately to focus on enhancing the accuracy of the treatment.

5. Soothing Care using Jaungo Modeling Pack

Immediately after the procedure, a Jaungo Modeling Pack is used

To help quickly alleviate minor skin irritation, redness, and heat sensations caused by the injection.

We provide finishing care to reduce excessive skin reactions and ensure a stable recovery process.

Recommended EndranHiller Treatment Cycle and Expected Duration

1. Initial Intensive Care (Recommended 3 sessions)

We generally recommend considering a total of 3 treatment sessions, spaced one month apart.

The treatment principle is simple.

This is because PN components must accumulate sufficiently in the dermis,

for the skin's fibroblasts to be activated,

and for the collagen regeneration process to proceed stably.

2. Maintenance Treatment (Retouch)

If you wish to prolong the effects of the treatment,

you may consider maintenance treatments about once every 6 months to a year.

Although there may be individual differences depending on skin condition and lifestyle,

generally, after receiving 3 treatment sessions, you can expect the effects to last for 6 to 12 months.

3. How long do the effects last?

After collagen regeneration is complete,

improvements in skin texture, elasticity, and inner skin density can be maintained for an average of 6 months or more.

However, the duration of maintenance may be somewhat shorter in the following cases:

When the skin is very thin or damaged.

When there are lifestyle habits that burden the skin, such as smoking or strong UV exposure.

4. When do the effects become noticeable?

Immediately after the treatment, temporary swelling or slight puffiness may appear.

After about 1 week, you may feel improved makeup adherence and a gradual refinement of skin texture.

In weeks 2-3, you can expect improved skin elasticity, increased density, and a reduction in fine lines.

After completing all 3 treatment sessions, you can visually observe or feel positive changes settling in the skin structure.

How painful is Endran Hiller?

Most describe it as a tolerable stinging sensation.

Since PN is injected directly into the dermis, it is not completely painless, but

with sufficient anesthesia, most patients complete the treatment comfortably.

Differences in pain by area

The cheeks, forehead, and around the mouth tend to have less discomfort.

The eye area, bridge of the nose, and chin may experience a momentary stinging sensation.

In areas with large pores, a heavy pressure may sometimes be felt.

Methods to minimize pain at our clinic

We ensure sufficient application time for anesthetic cream.

We adjust the injection speed, injecting slowly in small amounts.

We continuously check for any discomfort during the procedure.

We provide meticulous care, including a soothing pack after the treatment, until completion.

Recommended for Endran Hiller

1. Those with noticeably increased fine lines

When concerned about dense fine lines on the face, such as around the eyes, sides of the cheeks, and mouth.

It is suitable for those who desire natural wrinkle improvement without the burden of lifting or filler procedures.

2. Those whose skin becomes sensitive or easily red

Skin types that react sensitively even to cosmetic changes, or whose face often flushes red.

It can be beneficial for those who wish to restore weakened skin barriers to a healthy state.

3. Those who are concerned about inner skin dryness and makeup caking

If your skin feels oily on the surface but dry and tight underneath, and makeup tends to slide off easily, this treatment may be considered.

It may be suitable for those who feel a lack of moisture deep within their skin, even after consistent moisturizing care.

4. When skin vitality has decreased due to frequent treatments

Recommended for those whose skin has become thinner or more sensitive due to repeated laser or peeling treatments.

It can help when you want to restore your skin's natural health and firmness.

5. When you want to improve skin density and overall texture

It may be suitable for those who feel their skin is sagging or appears generally spread out due to loss of elasticity.

It's worth considering, especially if the contours of your cheekbones or cheeks are disturbed, and your skin texture feels rough.

Embossing Appearing After EndranHealer Treatment

A temporary raised bump on the skin, known as embossing, may appear in the area treated with EndranHealer.

This embossing can be understood as a positive sign that the medication has been effectively delivered to the skin's dermal layer.

The skin appearing slightly lumpy is a natural reaction, and it can indicate that the treatment effects are likely to manifest smoothly.

Most embossing typically subsides naturally within 1 to 2 days after the procedure.

If your skin is thin or dry, or if the treated area is sensitive like around the eyes or mouth, it may last for 2-3 days, up to a maximum of 4 days.

Rarely, it may persist for 5 to 7 days or longer, but

you generally do not need to worry much unless it is accompanied by significant pain, heat, or excessive redness.

In fact, this could indicate that the medication is being absorbed slowly, potentially providing positive effects on the skin for a longer period.

Post-Treatment Precautions

• ✔ Slight embossing, redness, and pain in the treated area may persist for about 2-3 days after the procedure.
• ✔ Please note that bruising, needle marks, and swelling due to injections may last for approximately 1-2 weeks after the procedure.
• ✔ For 7 days after the procedure, it is recommended to avoid alcohol, smoking, saunas, swimming pools, and strenuous exercise. This is to reduce the risk of skin irritation or inflammation.
• ✔ After the procedure, pay close attention to moisturizing care to help soothe your skin, and it is important to apply sunscreen thoroughly when going out.